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1

Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice

Ken-ichiro Kosai, Kunio Matsumoto, Hiroshi Funakoshi, Toshikazu Nakamura

Журнал:

Рік:

1999

Мова:

english

Файл:

PDF, 614 KB

english, 1999

2

Therapeutic effects of vitamin A on experimental cholestatic rats with hepatic fibrosis

Ken-ichi Murakami, Tatsuru Kaji, Ryuichi Shimono, Yoshihiro Hayashida, Hiroshi Matsufuji, Shinichiro Tsuyama, Rie Maezono, Ken-ichiro Kosai, Hideo Takamatsu

Журнал:

Pediatric Surgery International

Рік:

2011

Мова:

english

Файл:

PDF, 982 KB

english, 2011

3

Adenoviral-Mediated Herpes Simplex Virus-Thymidine Kinase Gene Transfer in Vivo for Treatment of Experimental Human Melanoma.

Bonnekoh, Bernd, Greenhalgh, David A., Bundman, Donnie S., Kosai, Ken-ichiro, Chen, Shu-Hsia, Finegold, Milton J., Krieg, Thomas, Woo, Savio L. C., Roop, Dennis R.

Журнал:

The Journal of Investigative Dermatology

Рік:

1996

Файл:

PDF, 2.29 MB

1996

4

APPLICATION OF AN ADENOVIRAL VECTOR ENCODING SOLUBLE TRANSFORMING GROWTH FACTOR-β TYPE II RECEPTOR TO THE TREATMENT OF DIABETIC NEPHROPATHY IN MICE

Takehito Kondo, Genzou Takemura, Ken-ichiro Kosai, Takamasa Ohno, Tomoyuki Takahashi, Masayasu Esaki, Kazuko Goto, Rumi Maruyama, Ichijiro Murata, Shinya Minatoguchi, Takako Fujiwara, Hisayoshi Fujiwa

Журнал:

Clinical and Experimental Pharmacology and Physiology

Рік:

2008

Мова:

english

Файл:

PDF, 204 KB

english, 2008

5

Hepatitis C virus RNA present in saliva but absent in breast-milk of the hepatitis C carrier mother

MASAYOSHI KAGE, SACHIKO OGASAWARA, KEN-ICHIRO KOSAI, EISUKE NAKASHIMA, KAZUHIDE SHIMAMATSU, MASAMICHI KOJIRO, AKIHIKO KIMURA, TAKUJI FUJISAWA, YOSHINORI MATSUKUMA, YUJI ITO, SHIGENOBU KONDO, KATSUICHI

Журнал:

Journal of Gastroenterology and Hepatology

Рік:

1997

Мова:

english

Файл:

PDF, 366 KB

english, 1997

6

Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function

Iida, Shin-ichi, Hirota, Toru, Morisaki, Tetsuro, Marumoto, Tomotoshi, Hara, Toshihiro, Kuninaka, Shinji, Honda, Shinobu, Kosai, Ken-ichiro, Kawasuji, Michio, Pallas, David C

Журнал:

Рік:

2004

Мова:

english

Файл:

PDF, 434 KB

english, 2004

7

An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice

Yasuhiro Terazaki, Shojiro Yano, Kentaro Yuge, Satoshi Nagano, Mari Fukunaga, Z.Sheng Guo, Setsuro Komiya, Kazuo Shirouzu, Ken-ichiro Kosai

Журнал:

Рік:

2003

Мова:

english

Файл:

PDF, 553 KB

english, 2003

8

Neural development of methyl-CpG-binding protein 2 null embryonic stem cells: A system for studying Rett syndrome

Yasunori Okabe, Akira Kusaga, Tomoyuki Takahashi, Chiaki Mitsumasu, Yoshinaka Murai, Eiichiro Tanaka, Hideho Higashi, Toyojiro Matsuishi, Ken-ichiro Kosai

Журнал:

Рік:

2010

Мова:

english

Файл:

PDF, 1.41 MB

english, 2010

9

Abrogation of Fas-Induced Fulminant Hepatic Failure in Mice by Hepatocyte Growth Factor

Ken-ichiro Kosai, Kunio Matsumoto, Shigekazu Nagata, Yoshihide Tsujimoto, Toshikazu Nakamura

Журнал:

Biochemical and Biophysical Research Communications

Рік:

1998

Мова:

english

Файл:

PDF, 5.47 MB

english, 1998

10

Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis: A novel antiangiogenic therapy

Taro Kamisasanuki, Saori Tokushige, Hiroto Terasaki, Ngin Cin Khai, Yuqing Wang, Taiji Sakamoto, Ken-ichiro Kosai

Журнал:

Biochemical and Biophysical Research Communications

Рік:

2011

Мова:

english

Файл:

PDF, 994 KB

english, 2011

11

In vivo hepatic HB-EGF gene transduction inhibits Fas-induced liver injury and induces liver regeneration in mice: A comparative study to HGF

Ngin Cin Khai, Tomoyuki Takahashi, Hiroaki Ushikoshi, Satoshi Nagano, Kentaro Yuge, Masayasu Esaki, Takao Kawai, Kazuko Goto, Yoshiteru Murofushi, Takako Fujiwara, Hisayoshi Fujiwara, Ken-ichiro Kosai

Журнал:

Journal of Hepatology

Рік:

2006

Мова:

english

Файл:

PDF, 673 KB

english, 2006

12

Adenoviral herpes simplex virus thymidine kinase gene therapy in an orthotopic lung cancer model

Mari Fukunaga, Shinzo Takamori, Akihiro Hayashi, Kazuo Shirouzu, Ken-ichiro Kosai

Журнал:

The Annals of Thoracic Surgery

Рік:

2002

Мова:

english

Файл:

PDF, 372 KB

english, 2002

13

Anti-Fas Gene Therapy Prevents Doxorubicin-Induced Acute Cardiotoxicity through Mechanisms Independent of Apoptosis

Shusaku Miyata, Genzou Takemura, Ken-ichiro Kosai, Tomoyuki Takahashi, Masayasu Esaki, Longhu Li, Hiromitsu Kanamori, Rumi Maruyama, Kazuko Goto, Akiko Tsujimoto, Toshiaki Takeyama, Tomonori Kawaguchi

Журнал:

The American Journal of Pathology

Рік:

2010

Мова:

english

Файл:

PDF, 1.58 MB

english, 2010

14

Recombinant soluble form of heparin-binding epidermal growth factor-like growth factor protein therapy drastically inhibits Fas-mediated fulminant hepatic failure: Implications in clinical application

Ngin Cin Khai, Kouichi Sakamoto, Hideo Takamatsu, Hiroshi Matsufuji, Ken-ichiro Kosai

Журнал:

Hepatology Research

Рік:

2011

Мова:

english

Файл:

PDF, 358 KB

english, 2011

15

Clinicopathological study of liver involvement in cytomegalovirus infection in infant autopsy cases

KEN-ICHIRO KOSAI, MASAYOSHI KAGE, MASAMICHI KOJIRO

Журнал:

Journal of Gastroenterology and Hepatology

Рік:

1991

Мова:

english

Файл:

PDF, 1.13 MB

english, 1991

16

Powerful and controllable angiogenesis by using gene-modified cells expressing human hepatocyte growth factor and thymidine kinase

Yasuyo Hisaka, Masaki Ieda, Toshikazu Nakamura, Ken-ichiro Kosai, Satoshi Ogawa, Keiichi Fukuda

Журнал:

Journal of the American College of Cardiology

Рік:

2004

Мова:

english

Файл:

PDF, 392 KB

english, 2004

17

Leptin gene therapy in the fight against diabetes

Wang, Yuqing, Asakawa, Akihiro, Inui, Akio, Kosai, Ken-ichiro

Журнал:

Expert Opinion on Biological Therapy

Рік:

2010

Мова:

english

Файл:

PDF, 247 KB

english, 2010

18

Survivin-responsive conditionally replicating adenovirus kills rhabdomyosarcoma stem cells more efficiently than their progeny

Tanoue, Kiyonori, Wang, Yuqing, Ikeda, Minako, Mitsui, Kaoru, Irie, Rie, Setoguchi, Takao, Komiya, Setsuro, Natsugoe, Shoji, Kosai, Ken-ichiro

Журнал:

Journal of Translational Medicine

Рік:

2014

Мова:

english

Файл:

PDF, 1.38 MB

english, 2014

19

Hepatitis C virus RNA in saliva and breastmilk of hepatitis C carrier mothers

Ogasawara, Sachiko, Kage, Masayoshi, Kosai, Ken-Ichiro, Shimamatsu, Kazuhide, Kojiro, Masamichi

Журнал:

Рік:

1993

Мова:

english

Файл:

PDF, 122 KB

english, 1993

20

Adenovirus-Mediated Interleukin-12 Gene Therapy for Metastatic Colon Carcinoma

Manuel Caruso, Khiem Pham-Nguyen, Yok-Lam Kwong, Bisong Xu, Ken-Ichiro Kosai, Milton Finegold, Savio L. C. Woo and Shu-Hsia Chen

Журнал:

Proceedings of the National Academy of Sciences

Рік:

1996

Мова:

english

Файл:

PDF, 1.16 MB

english, 1996

21

Retrovirus-Mediated In Vivo Gene Transfer in the Replicating Liver Using Recombinant Hepatocyte Growth Factor Without Liver Injury or Partial Hepatectomy

Kosai, Ken-Ichiro, Finegold, Milton J., Thi-Huynh, Bich-Thuy, Tewson, Margaret, Ou, Ching-Nan, Bowles, Neil, Woo, Savio L. C., Schwall, Ralph H., Darlington, Gretchen J.

Журнал:

Human Gene Therapy

Рік:

1998

Мова:

english

Файл:

PDF, 4.77 MB

english, 1998

22

588. Hepatic HB-EGF (Heparin-Binding EGF-Like Growth Factor) Gene Therapy for Fulminant Hepatic Failure in Mice: More Potent Protective and Mitogenic Effects for Hepatocytes Than HGF (Hepatocyte Growth Factor)

Kosai, Ken-ichiro, Cin Khai, Ngin, Takahashi, Tomoyuki

Журнал:

Molecular Therapy

Рік:

2006

Мова:

english

Файл:

PDF, 113 KB

english, 2006

23

Hepatocyte Growth Factor Gene Therapy Slows Down the Progression of Diabetic Nephropathy in db/db Mice

Kagawa, Tomoyo, Takemura, Genzou, Kosai, Ken-ichiro, Murata, Ichijiro, Ohno, Takamasa, Takahashi, Tomoyuki, Esaki, Masayasu, Maruyama, Rumi, Fujiwara, Takako, Ohashi, Hiroshige, Fujiwara, Hisayoshi

Журнал:

Nephron Physiology

Рік:

2006

Мова:

english

Файл:

PDF, 2.48 MB

english, 2006

24

FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure

Hino, Shinjiro, Sakamoto, Akihisa, Nagaoka, Katsuya, Anan, Kotaro, Wang, Yuqing, Mimasu, Shinya, Umehara, Takashi, Yokoyama, Shigeyuki, Kosai, Ken-ichiro, Nakao, Mitsuyoshi

Журнал:

Nature Communications

Рік:

2012

Мова:

english

Файл:

PDF, 1.04 MB

english, 2012

25

The Role of Interleukin-2 in Combination Adenovirus Gene Therapy for Head and Neck Cancer

O’Malley, Bert W., Sewell, Duane A., Li, Daqing, Kosai, Ken-ichiro, Chen, Shu-Hsia, Woo, Savio L.C., Duan, Ling

Журнал:

Molecular Endocrinology

Рік:

1997

Мова:

english

Файл:

PDF, 1.47 MB

english, 1997

26

Gene therapy eradicating distant disseminated micro-metastases by optimal cytokine expression in the primary lesion only: Novel concepts for successful cytokine gene therapy

Nagano, Satoshi, Yuge, Kentaro, Fukunaga, Mari, Terazaki, Yasuhiro, Fujiwara, Hisayoshi, Komiya, Setsuro, Kosai, Ken-Ichiro

Журнал:

International Journal of Oncology

Рік:

2004

Мова:

english

Файл:

PDF, 3.05 MB

english, 2004

27

Adenoviral gene transduction of hepatocyte growth factor elicits inhibitory effects for hepatoma

Yuge, Kentaro, Takahashi, Tomoyuki, Nagano, Satoshi, Terazaki, Yasuhiro, Murofushi, Yoshiteru, Ushikoshi, Hiroaki, Kawai, Takao, Khai, Ngin, Nakamura, Toshikazu, Fujiwara, Hisayoshi, Kosai, Ken-Ichiro

Журнал:

International Journal of Oncology

Рік:

2005

Мова:

english

Файл:

PDF, 2.48 MB

english, 2005

28

Diffuse encephaloventriculitis and substantial leukoencephalopathy after intraventricular administration of recombinant adenovirus

Tada, Tsuyoshi, Nguyen, John Bang, Hitoshi, Yasuyuki, Watson, Nathan P., Dunn, Jeffrey F., Ohara, Shinji, Nagano, Satoshi, Kosai, Ken-ichiro, Israel, Mark A.

Журнал:

Neurological Research

Рік:

2005

Мова:

english

Файл:

PDF, 845 KB

english, 2005

29

Combination Gene Therapy for Liver Metastasis of Colon Carcinoma in vivo

Shu-Hsai Chen, X. H. Li Chen, Yibin Wang, Ken-Ichiro Kosai, Milton J. Finegold and Susan S. Rich

Журнал:

Proceedings of the National Academy of Sciences

Рік:

1995

Мова:

english

Файл:

PDF, 1.26 MB

english, 1995

30

Genetic Modification of Hepatocytes Towards Hepatocyte Transplantation and Liver Tissue Engineering

Kuge, Hiroyuki, Ohashi, Kazuo, Yokoyama, Takashi, Kanehiro, Hiromichi, Hisanaga, Michiyoshi, Koyama, Fumikazu, Bumgardner, Ginny L., Kosai, Ken-Ichiro, Nakajima, Yoshiyuki

Журнал:

Cell Transplantation

Рік:

2006

Мова:

english

Файл:

PDF, 309 KB

english, 2006

31

Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition

Miyazaki, Yumi, Matsubara, Shyuichirou, Ding, Qiang, Tsukasa, Koichiro, Yoshimitsu, Makoto, Kosai, Ken-ichiro, Takao, Sonshin

Журнал:

Molecular Cancer

Рік:

2016

Мова:

english

Файл:

PDF, 1.29 MB

english, 2016

32

Adenoviral-Mediated Herpes Simplex Virus Thymidine Kinase Gene Transfer

Block, Andreas, Chen, Shu-Hsia, Kosai, Ken-Ichiro, Finegold, Milton, Woo, Savio L. C.

Журнал:

Рік:

1997

Мова:

english

Файл:

PDF, 2.39 MB

english, 1997

33

Cell cycle-specific changes in hTERT promoter activity in normal and cancerous cells in adenoviral gene therapy: A promising implication of telomerase-dependent targeted cancer gene therapy

Murofushi, Yoshiteru, Nagano, Satoshi, Kamizono, Junichi, Takahashi, Tomoyuki, Fujiwara, Hisayoshi, Komiya, Setsuro, Matsuishi, Toyojiro, Kosai, Ken-ichiro

Журнал:

International Journal of Oncology

Рік:

2006

Мова:

english

Файл:

PDF, 246 KB

english, 2006

34

Efficient Cardiomyogenic Differentiation of Embryonic Stem Cell by Fibroblast Growth Factor 2 and Bone Morphogenetic Protein 2

Kawai, Takao, Takahashi, Tomoyuki, Esaki, Masayasu, Ushikoshi, Hiroaki, Nagano, Satoshi, Fujiwara, Hisayoshi, Kosai, Ken-ichiro

Журнал:

Circulation Journal

Рік:

2004

Мова:

english

Файл:

PDF, 2.77 MB

english, 2004

35

Heparin-binding epidermal growth factor-like growth factor and hepatocyte growth factor inhibit cholestatic liver injury in mice through different mechanisms

Sakamoto, Kouichi, Khai, Ngin, Wang, Yuqing, Irie, Rie, Takamatsu, Hideo, Matsufuji, Hiroshi, Kosai, Ken-Ichiro

Журнал:

International Journal of Molecular Medicine

Рік:

2016

Мова:

english

Файл:

PDF, 913 KB

english, 2016

36

241. An Efficient Construction of Lentiviral Vectors That Identify and Eliminate Tumorigenic Cells in Pluripotent Stem Cells

Ide, Kanako, Mitsui, Kaoru, Kosai, Ken-ichiro

Журнал:

Molecular Therapy

Рік:

2016

Мова:

english

Файл:

PDF, 1.08 MB

english, 2016

37

414. A Novel System to Systematically Analyze Diverse Types of Conditionally Replicating Adenoviruses Expressing Immunostimulatory Genes in Syngenic Hamster Models

Ijichi, Nobuhiro, Kawakami, Hirotaka, Obama, Yuki, Kosai, Ken-ichiro

Журнал:

Molecular Therapy

Рік:

2016

Мова:

english

Файл:

PDF, 1.20 MB

english, 2016

38

Viral Vector-Based Innovative Approaches to Directly Abolishing Tumorigenic Pluripotent Stem Cells for Safer Regenerative Medicine

Mitsui, Kaoru, Ide, Kanako, Takahashi, Tomoyuki, Kosai, Ken-ichiro

Журнал:

Molecular Therapy — Methods & Clinical Development

Рік:

2017

Мова:

english

Файл:

PDF, 2.26 MB

english, 2017

39

Pathogenesis of Lethal Aspiration Pneumonia in Mecp2-null Mouse Model for Rett Syndrome

Kida, Hiroshi, Takahashi, Tomoyuki, Nakamura, Yuki, Kinoshita, Takashi, Hara, Munetsugu, Okamoto, Masaki, Okayama, Satoko, Nakamura, Keiichiro, Kosai, Ken-ichiro, Taniwaki, Takayuki, Yamashita, Yushir

Журнал:

Scientific Reports

Рік:

2017

Мова:

english

Файл:

PDF, 9.01 MB

english, 2017

40

A Novel construction of lentiviral vectors for eliminating tumorigenic cells from pluripotent stem cells

Ide, Kanako, Mitsui, Kaoru, Irie, Rie, Matsushita, Yohei, Ijichi, Nobuhiro, Toyodome, Soichiro, Kosai, Ken-ichiro

Журнал:

Рік:

2017

Мова:

english

Файл:

PDF, 749 KB

english, 2017

41

Conditionally replicating adenovirus prevents pluripotent stem cell–derived teratoma by specifically eliminating undifferentiated cells

Mitsui, Kaoru, Ide, Kanako, Takayama, Akiko, Wada, Tadahisa, Irie, Rie, Kosai, Ken-ichiro

Журнал:

Molecular Therapy — Methods & Clinical Development

Рік:

2015

Мова:

english

Файл:

PDF, 4.86 MB

english, 2015

42

Intramuscular injection of adenoviral hepatocyte growth factor at a distal site ameliorates dextran sodium sulfate-induced colitis in mice

YUGE, KENTARO, TAKAHASHI, TOMOYUKI, KHAI, NGIN CIN, GOTO, KAZUKO, FUJIWARA, TAKAKO, FUJIWARA, HISAYOSHI, KOSAI, KEN-ICHIRO

Журнал:

International Journal of Molecular Medicine

Рік:

2014

Файл:

PDF, 921 KB

2014

43

A survivin-responsive, conditionally replicating adenovirus induces potent cytocidal effects in adult T-cell leukemia/lymphoma

Suzuki, Shinsuke, Kofune, Hiroki, Uozumi, Kimiharu, Yoshimitsu, Makoto, Arima, Naomichi, Ishitsuka, Kenji, Ueno, Shin-ichi, Kosai, Ken-ichiro

Журнал:

Рік:

2019

Мова:

english

Файл:

PDF, 1.03 MB

english, 2019